Radiolabeling and Quantitative In Vivo SPECT/CT Imaging Study of Liposomes Using the Novel Iminothiolane-99mTc-Tricarbonyl Complex
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منابع مشابه
Radiolabeling and Quantitative In Vivo SPECT/CT Imaging Study of Liposomes Using the Novel Iminothiolane-99mTc-Tricarbonyl Complex
The in vivo biodistribution of liposomal formulations greatly influences the pharmacokinetics of these novel drugs; therefore the radioisotope labeling of liposomes and the use of nuclear imaging methods for in vivo studies are of great interest. In the present work, a new procedure for the surface labeling of liposomes is presented using the novel 99mTc-tricarbonyl complex. Liposomes mimicking...
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In recent years, the diagnostic and therapeutic uses of radioisotopes have shown significant progress. Immunoglobulin (Ig) appears to be a promising tracer, particularly due to its ability to target selected antigens. The main objective of this study is to optimize and assess an Ig radiolabeling method with Technetium 99m (99mTc), an attractive radioelement used widely for diagnostic imaging. M...
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15 صفحه اولNano Liposomes labeled with 99mTc-HMPAO, A Novel Agent for Blood Pool Imaging
In-vitro labeling of RBC with 99mTc is an intricate procedure and there is always a need foran alternate blood pool imaging agent. The aim of this study was to prepare an effective nanosized liposome (NLs) similar to human RBC for blood pool scintigraphy. This study formulatesPEG-NLs and non-PEG-NLs using film method plus high pressure homogenization technique.Biodistribution studies were perfo...
متن کاملNano Liposomes labeled with 99mTc-HMPAO, A Novel Agent for Blood Pool Imaging
In-vitro labeling of RBC with 99mTc is an intricate procedure and there is always a need foran alternate blood pool imaging agent. The aim of this study was to prepare an effective nanosized liposome (NLs) similar to human RBC for blood pool scintigraphy. This study formulatesPEG-NLs and non-PEG-NLs using film method plus high pressure homogenization technique.Biodistribution studies were perfo...
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ژورنال
عنوان ژورنال: Contrast Media & Molecular Imaging
سال: 2017
ISSN: 1555-4309,1555-4317
DOI: 10.1155/2017/4693417